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CL-82198

發(fā)布日期:2017-10-26   瀏覽次數(shù):0
核心提示:a href=https://www.medchemexpress.com/CL-82198.htmlCL-82198/a產(chǎn)品描述:CL-82198 is a selective inhibitor of MMP-13.In vi
<a href="https://www.medchemexpress.com/CL-82198.html">CL-82198</a>產(chǎn)品描述:CL-82198 is a selective inhibitor of MMP-13.

In vitro: In the presence of 10 and 20 μM of the specific MMP-13 inhibitor, CL-82198, migration of the LS174 cells was significantly reduced by 55 and 52%, respectively. . CL-82198 binds to the S1' pocket of MMP-13 leading to 89% enzyme inhibition at a concentration of 10 μg/ml. The addition of the specific MMP-13 inhibitor CL-82198 at a concentration of 10 μM resulted in a 45±5.6% reduction in the migration of LS174 cells.

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src="http://img.dxycdn.com/trademd/upload/userfiles/image/2014/08/A1408605159png_small.jpg"

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